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The high levels of ferryl Hb content within MPs were correlated with complex formation with band 3 and RBC membrane proteins (Figure 1)

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Since NKG2D recognizes vastly different fungi, we hypothesized that the ligand might be a common glycan and not a protein, as one highly conserved ligand is more likely than a group of ligands, and common cell-wall carbohydrates tend to be better conserved than proteins across the diverse fungal evolutionary tree