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Hu Q, Zhang H, Gutirrez Corts N, Wu D, Wang P, Zhang J, et al

Without adequate collagen production and remodeling, injuries to these tissues struggle to regenerate properly, often resulting in scar tissue thats weaker and less functional than the original tissue

The collagen fiber type transitions gradually from the outer to the inner layersthe outer layer is primarily composed of tension-resistant type I collagen, while moving inward, it gradually mixes with type II collagen extending to the edge of the nucleus pulposus, forming a tough ring structure that provides mechanical support to the disc by restricting NP displacement and resisting compressive loads

Language experience during infancy predicts white matter myelination at age 2 years

Dimethyl itaconate is effective in host-directed antimicrobial responses against mycobacterial infections through multifaceted innate immune pathways