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The NLRP3 complex promotes the cleavage of pro-caspase-1 into active caspase-1, facilitating the maturation and release of IL-1 and IL-18, amplifying inflammation and pyroptosis within the ovarian microenvironment (Yin et al

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NF-B affects cell survival and has a role in the development of mood disorders (Wohleb et al., 2011

This observation contributes to the growing body of evidence that supports H 2 O 2 as a causal factor in the pathogenesis of UC