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635 A double-blind, randomized, placebo-controlled trial of LX-9211 for pain relief and safety in DPN initially found that LX-9211 improved PDPN

Some of them, such as the already-mentioned T2DM, along with hyperlipidemia or hypertension, comprise metabolic syndrome [21], eventually increasing cardiovascular risk and, hence, potentially resulting in ischemic heart disease and ischemic or hemorrhagic stroke [22]

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To determine the total carnitine content, alkaline hydrolysis is typically required