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Aberrant light cycles can modify gut microbiota composition, altering especially relative abundance of Lactobacillus and Bacteroidetes [348]

2 Folate supplementation can correct these haematological effects of B12 deficiency but not the neurological complications, which include neuropathies, such as tingling and numbness in the arms and legs, sensory and motor disturbances, including abnormal gait, and cognitive changes

The honest, scientifically-grounded answer is this: the preclinical evidence is compelling and provides a strong rationale for further investigation

References 1 AdachiY.MooreL

Restricting intake of potassium-rich fruits and vegetables inhibits the conversion of fermentable dietary fiber to SCFAs, leading to gut microbiota dysbiosis and increased intestinal protein fermentation, thereby increasing the formation of gut-derived uremic toxins (109)

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