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However, it is uncommon and challenging to statistically assess the combination of clinical, imaging, biochemical, pathological, genetic, and electrophysiological markers

For example, the down-regulation of PAQR3 (progestin and adipoQ receptor family member III) expression in BC tissues is significantly associated with abnormal methylation of gene promoters ( APC and RARB genes can be detected in serum samples from patients with early BC (Swellam et al., 2015)

Second, the three hallmarks of ferroptosis, iron dysregulation, lipid peroxidation, and antioxidant system failure, are evident in BD patients

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An 18-year follow-up