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Subsequently, when macrophages attempt to phagocytize MSU crystals, the sharp structure of the crystals causes lysosomal membrane rupture

Excessive mitochondrial biogenesis may exacerbate oxygen demand in hypoxic regions, and mPTP inhibition could inadvertently shield damaged mitochondria from mitophagy

Rapid urbanization is intensifying this trend, as city dwellers actively seek nutritional interventions to combat oxidative stress, environmental pollution exposure, and immune system challenges

Primary infection is generally asymptomatic

This could increase how much lithium is in the body and result in serious side effects