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Interestingly, recent studies indicate that in the setting of ATII-induced hypertension, a downregulation of the dihydrofolate reductase was observed, which was accompanied by decreased vascular BH 4 levels and an uncoupled eNOS, 91 implicating a potential role of this salvage pathway in the development of hypertension

Available from: Bonomini M, Del Vecchio L, Sirolli V, Locatelli F

doi: 10.1002/alz.14541 124 ValentiniE.Di MartileM.BrignoneM.Di CaprioM.ManniI.ChiappaM.et al

In this study, the occurrence of mastocytosis, as characterized by the presence of proliferating and hyperactivated mast cells in several organs, is investigated in children with ASD (55)