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Gastrointestinal disorders were the most common adverse events with semaglutide, typically transient, of mild-to-moderate severity, occurring during dose escalation, and infrequently leading to treatment discontinuation

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Analysis of the data indicates that short-term treatment with RM-493 increased resting energy expenditure significantly (by 6.4% vs placebo), thus suggesting RM-493 may be clinically effective for treating obesity

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FDA Approved?: No Life Stage: All life stages Brand Names: Cobalequin (chewable tablets) Common Names: Cyanocobalamin, Vitamin B12 Available Dosages: Chewable tablets in 250 mcg, and 1000 mcg