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Bergsbaken T, Fink SL, Cookson BT

10.1002/ptr.6647 67 JiangH.WangL.ZhangQ.WangS.JiaL.ChengH.et al (2024)

Nevertheless, targeting nutrients alone does not seem to confer benefits because of exogenous nutrient uptake

Because of these properties, the matrix both physically slows the diffusion of antifungal agents and chemically interacts with them (for example, binding azoles or polyenes), thereby reducing the effective antifungal exposure to cells embedded deep in the biofilm (Nett and Andes, 2020