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Identification of Retinoic Acid as an Inhibitor of Transcription Factor Nrf2 through Activation of Retinoic Acid Receptor Alpha

Rees DC, Williams TN, Gladwin MT

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If your moisturizer has active ingredients like retinoids, salicylic acid, and alpha-hydroxy acids (AHAs), such as glycolic acid and lactic acid, then yes

If injected incorrectly, tissue ischemia may be one of the issues to occur