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Compared to existing diagnostic methods like FeNO and sputum eosinophilia, ferroptosis-related biomarkers offer potential advantages in identifying novel endotypes, predicting steroid resistance, and reflecting distinct pathophysiological processes

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The successful interaction between Nrf2 and the ARE/EpRE (electrophilic response element) and the formation of a heterodimer between Nrf2 and minor Maf proteins (MafG, MafK, and MafF) are essential for the expression of Nrf2-controlled genes [44]

Practical tips Before full application, perform a test on a small area of skin to rule out allergic reaction

Bonnefont-Rousselot, D., Raji, B., Walrand, S., Gardes-Albert, M., Jore, D., and Legrand, A., Metabolism , 2003, vol