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Biomechanical testing After 3 weeks, the repaired Achilles tendon ( n = 16) and the contralateral control tendons ( n = 16) were harvested for mechanical evaluation

The accumulation of Fe2+ and Fe3+ signifies an iron overload due to excessive iron build-up, and this is a key factor in ferroptosis (15)

doi: 10.3389/fimmu.2026.1735598 Received 30 October 2025 Revised 03 February 2026 Accepted 04 February 2026 Published 18 February 2026 Volume 17 - 2026 Edited by Diego Kauffmann-Guerrero, LMU Munich University Hospital, Germany Reviewed by Anthony De Soyza, Newcastle University, United Kingdom Susanne Nhrig, LMU Munich University Hospital, Germany Updates Copyright 2026 Yu, Zhu, Jin, Ding and Jin