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The rutaecarpine (8, 13-dihydroindolo- [2, 3:3, 4]-pyrido [2, 1-b] quinazolin-5(7H)-one) is an indolopyridoquinazoline alkaloid [41] isolated from Evodia rutaecarpa by ketone extraction (Lee et al., 2008)

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Isolation of primary renal tubular epithelial cells (TECs) Primary mouse renal tubular epithelial cells were isolated using an established protocol we previously published 9