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Jomova, K

Pathways of mitochondrial transfer The intercellular transfer of mitochondria, a crucial compensatory mechanism in pathological conditions such as IS [17, 18], is mediated through multiple highly coordinated pathways including [1] tunneling nanotubes (TNTs) [2], extracellular vesicles (EVs) [3], connexin 43 (Cx43)-mediated gap junctions, and [4] direct membrane fusion processes [19, 20]

The purpose of the present mini-review is to discuss the potential efficiency of some pharmacologically known antidotes in alleviating the clinical manifestations of COVID-19 contagion with a brief discussion of their mechanisms to counteract the symptoms of COVID-19 infection

Conversely, in neuroinflammatory diseases, astrocytes are excessively activated into a neurotoxic state by cytokines secreted by microglia, releasing uncontrolled pro-inflammatory cytokines and complement proteins, which exacerbate damage to neighboring cells (6,7)

Importantly, we also determined the effect of NAC treatment on host inflammatory responses to urease and P