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The NIH Office of Dietary Supplements and the American Academy of Family Physicians identify the following groups as most vulnerable: Adults over 50 Age-related decline in stomach acid production reduces the ability to release B12 from food proteins

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If you're forgetful, or circumstances make it hard for you to stick with it, the injections may be the better way to go

Medications: acid-reflux drugs (PPIs) and some diabetes medications (such as metformin) can interfere with B12 absorption