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GST is utilized as a fusion protein with foreign proteins in a range of prokaryotic expression vectors, including the pGEX family of vectors

Fatty acid metabolites produced by gut microbiota, such as SCFAs, can cross the blood-brain barrier and influence the hypothalamic-pituitary-adrenal (HPA) axis, stimulating the secretion of gut hormones such as glucagon-like peptide-1 (GLP-1) and peptide tyrosine tyrosine (PYY), which in turn regulate lipid metabolism and inflammatory responses [192, 193]

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Additionally, a KD may modulate the immune system and result in reduced inflammation

Patients were categorized into four groups based on their serum PIVKA-II (cut-off value 1500 mAU/mL) and AFP (cut-off value 20 ng/mL) levels at diagnosis