guaiacol peroxidase and glutathione peroxidase Oxidative stress in Portuguese children with Down syndrome Oxidation of guaiacol to tetraguaiacol,

superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), -glutamyltransferase (-GT), carnitine palmitoyltransferase 1 (CPT-1), lactate dehydrogenase (LDH), heme oxygenase-1 (HO-1), xanthine oxidase (XO)

Glutathione S -transferase enzymes catalyze its conjugation to lipophilic xenobiotics, facilitating their excretion or further metabolism

For example, in a mouse model of lipopolysaccharide-induced neuro-inflammation and Alzheimers disease, FMN supplementation with specific nanoparticles targeting riboflavin metabolism in the microglia ameliorated cognitive dysfunction, synaptic plasticity, and inflammation 71

Hydrogen peroxide (H2O2)

Glutathione supplement capsules contained 500mg of L-glutathione (fermentation) together with 250mg of ascorbic acid, 50mg of ALA, and 4mg (20mg) of zinc (as zinc aspartate) as additional ingredients, whereas the placebo capsules contained glucose powder in a gelatin coating