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and continuous pro-synthetic signaling can tip toward fibrosis and scarring rather than functional repair

Wu, C., An, W., Liu, Z., Lin, J., & Qian, Z

(70) utilized a network pharmacological approach to predict anti-renal tubulointerstitial fibrosis effects via the ERK1/2 signaling pathway, a finding later confirmed in human renal tubular epithelial cells induced by high glucose

Other studies have focused on the leaves, resulting in the extraction of three new iridoids, one of which exhibited inhibitory effects on the lung cancer cell line A-549 (52)

However, progression through the translational pipeline is impeded by various obstacles