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doi: 10.1111/epi.16813 20 CitraroR.LeoA.De CaroC.NesciV.Gallo CantafioM

Preclinical work commonly screens low-micromolar ranges (e.g., 130 M) for pathway readouts such as 1-MNA reduction and lipogenesis suppression

By reactivating partial telomerase expression, epithalon has been shown in fibroblast cultures to extend telomere length and push cells past the Hayflick limit by 10+ additional doublings