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GPx isoenzymes are all antioxidant enzymes that reduce potentially damaging reactive oxygen species (ROS), such as hydrogen peroxide and lipid hydroperoxides, to harmless products like water and alcohols by coupling their reduction with the oxidation of glutathione (Figure 2a )

In addition, we discuss the discovery of biological targets associated with the BBB to provide a reference for further improvement of epilepsy treatment strategies in the future

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Hannon R, Croxtall JD, Getting SJ, Roviezzo F, Yona S, Paul-Clark MJ et al (2003)

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