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10.1034/j.1600-0838.2001.110606.x 57 HartmanM

As aforementioned, the effects on redox balance favoring more oxidation can reduce the antioxidant capacity in the circulation and damage protective mechanisms

Calcium modulation and high calcium permeability of neuronal nicotinic acetylcholine receptors

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229,230 Interestingly, in a patient with SCO2 mutations who presented with severe hypertrophic cardiomyopathy, Cu-histidine supplementation has been reported to improve heart function, showing attenuated cardiomyopathy as well as the normalization of blood pressure