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[DOI] [PubMed] [Google Scholar] Fujimori M., Kadota K., Shimono K., Shirakawa Y., Sato H., Tozuka Y

In agreement, JMF4073 sensitivity was higher in K562, less in TCCS, and insensitive in KOPM28 (Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] 182.de la Fuente M., Lombardero L., Gmez-Gonzlez A., Solari C., Angulo-Barturen I., Acera A., Vecino E., Astigarraga E., Barreda-Gmez G

In addition to tissue growth promotion, hGH modulates body fat composition as well as carbohydrate and protein metabolism.15 In adipose tissue, hGH induces breakdown of triglycerides by stimulating hormone-sensitive lipase and also inhibits glucose uptake which is essential for adipocyte differentiation.16 Moreover, hGH is an autocrine oncogenic factor that promotes the proliferation of breast cancer stem cells.17 Therefore, hGH-related peptides may be extremely beneficial in drug targeting and possibly for disrupting hGH-dependent breast cancer progression as well

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