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First, mAbs are produced in eukaryotic cell lines because of their complex expression and post-translational modifications, increasing the cost of production [105]

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Based on in vitro evidence and evidence in models of ovarian cancer, melanoma, and glioma, the researchers are planning to launch a phase I clinical trial in which nanoparticles will be delivered intraperitoneally to patients with chemotherapy-resistant ovarian carcinoma

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