methylglyoxal glutathione reductase Model illustrating the metabolism and detoxification glutathione reductase activity assay Methylglyoxal and Its Adducts: Induction,

3 Oxidative Stress Is Higher When Glutathione Runs Low Lower glutathione levels are associated with increased oxidative stress, placing additional strain on detox and cellular processes like methylation

doi:10.1111/j.1472-8206.2008.00638.x, PMID: 19207541 Kumar A, Garg R (2008) Kumar P (2008) Nitric oxide modulation mediates the protective effect of trazodone in a mouse model of chronic fatigue syndrome

Simulations suggest that glutathione pools are most sensitive to exposure duration at pharmacologically and supra-pharmacologically relevant doxorubicin concentrations

L-theanine is a calming amino acid found mostly in green tea, black tea, white tea and matcha

Owing to the velocity of blood movement through the voxel, MRS does not detect GSH signal from blood, thus, the measured GSH values reflect only GSH in brain parenchyma or CSF