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SKU: 1354081838
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Availability: InStock
Rating: 4.4239 (14 reviews)

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n = 6), or in medium containing 5% FBS ( n = 8)

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In canonical Wnt/-catenin signaling, the secreted Wnt ligands bind with the Frizzled receptor, which further inactivates glycogen synthase kinase-3 (GSK-3), which is an enzyme responsible for the ubiquitination-mediated degradation of -catenin 4,5