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As a result of mitochondrial dysfunction, cell damage and DNA repair system impairment occur [52]

[DOI] [PubMed] [Google Scholar] Cheng L

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171 unravelled Zaprinast, a phosphodiesterase 5 inhibitor, as a potent inhibitor of mutant IDH1 R132C -mediated 2-HG biosynthesis in HT1080 cells

*Correspondence: Ren-You Gan, [email protected] Wu, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Food Chemistry, a section of the journal Frontiers in Nutrition Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers