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Protects against external environment factors with naturally occurring vitamins A

Multiple signaling molecules regulate cardiovascular energy metabolism, playing key roles in the transcription of metabolism-related genes, including AMPK, PGC-1, SIRT, and PPARs

In contrast, decreased expression of mitochondrial ferritin can initiate mitochondrial autophagy through the ROS/PINK1/Parkin pathway, leading to the accumulation of ferritin and the enhancement of ferroptosis in osteoblasts ( Figure 3 ) (135)

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Caggiu E, Paulus K, Mameli G, Arru G, Sechi GP, Sechi LA (2018) Differential expression of miRNA 155 and miRNA 146a in Parkinsons disease patients