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Yang Constitutive intestinal NF-kB does not trigger destructive inflammation unless accompanied by MAPK activation J Exp Med

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Jul 17 2013;105(14):1027-1035

A recent study suggested that hypobaric hypoxia at high-altitude induces both apoptosis and ferroptosis via the JNK signaling pathway by depleting keratin 18 (Krt18) and elevating JNK3 (MAPK10), as well as increasing ASCL4 for ferroptosis [136]