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Proteins were visualized using fluorescent dye-conjugated secondary antibodies (Li-Cor, 800CW or 680LT), and signal intensity analysis was performed using Image Studio suite (Li-Cor)

2012;9:1-9 Jacob M Wilson et

This review elucidates the modification process and molecular biological significance of lactylation, as well as its involvement in various physiologies and multiple diseases, describes the potential of lactylation as a biomarker for diagnosis and prognosis, and emphasizes the promise of lactylation-targeted therapies

As recently demonstrated by Rishniw and Brown, approximately 10% of healthy CKCSs would be misclassified as having LV enlargement using the ACVIM-recommended scaling exponent (0.294) and the cut-off of 1.7 for normalized end-diastolic LV internal diameter

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