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118,119 The pathogenesis of DR is complex, with emerging evidence highlighting the role of premature senescence in retinal cells and the secretion of inflammatory cytokines that exacerbate disease progression through paracrine senescence and pathological angiogenesis

In particular, the relationship between psoriasis and obesity is bidirectional, with obesity favoring psoriasis and psoriasis predisposing individuals to obesity (Shipman and Millington, 2011

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