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2019;149: w20129

However, the largest Phase IIb trial involving 536 participants failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading to development termination in 2007

Although Novo underscored that patients in the trial achieved up to 22.7% of weight loss with CagriSema, analysts previously said they were hoping to see whether it would significantly beat Lillys Zepbound

As of this writing, neither cagrilintide monotherapy nor the CagriSema combination is approved for any indication anywhere, and it may not be prescribed or sold for human use

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