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Catalpol also exerts protective effects against septic acute kidney injury by modulating Sirtuin 1 (SIRT1) and Nuclear Factor erythroid 2 (Nrf2)/Heme Oxygenase (HO-1) signaling pathways, synergistically promoting antioxidant and anti-inflammatory responses and alleviating sepsis-induced organ dysfunction in LPS-treated mice (Zhang and Qiang, 2023)

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