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Docking simulations on inactive BAX (PDB code 4S0O) with the sequence WVELHFSN and the sequence with S-to-F substitution, WVELHFFN, with HADDOCK showed that both peptides are predominantly placed over the N-terminal end of the BAX -helix 5 (Supplementary Fig

In terms of electronic interaction, ACQgens with planar conformation own covalently through-bond conjugation (TBC), which show intrinsic single-molecule emission in dilute solution and suffer the quenching effect in the aggregate state 24,25

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