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Table 1 links recurrent TME phenotypes to dominant barriers, design objectives, candidate nanotherapeutic strategies and key translational cautions

A standard 6-week treatment protocol at 0.5 mg daily requires approximately 21 mg total, or about 4-5 vials

Another group found that silencing either ALOX15B or ALOXE3 prevented erastin-induced cell death, which supported the hypothesis that LOXs are required for ferroptosis initiated by class 1 inducers [12]

Eur J Endocrinol 185(4):G43G67 Smith TJ, Bartalena L (2019) Will biological agents supplant systemic glucocorticoids as the first-line treatment for thyroid-associated ophthalmopathy