l-carnitine hc1 400 mg alpha lipoic acid 200 mg Acetyl HCL & 1200mg per serving Acetyl L-Carnitine & Alpha-Lipoic Acid,

P., Nobuo, M., da Costa Miranda, M., Schlinder, F., Riechelmann, R., & del Giglio, A

Liss, New York, 1983

Subacute Toxicity Maximum no-effect dose in rats: 450 mg/kg, cecal enlargement, increased K+ and Cl- in urine

E N D Presentation Transcript L-Carnitine Charisma Garcia NFSC 345 Introduction Background Purported Benefits Mechanism of Action Evidence of Benefits Conflicting Research Safety Concerns Professional Position L-Carnitine Essential for Energy Production Naturally Occurs in the Human Body Synthesized in the Liver & Kidneys Derived from the amino acid, Lysine Produces 11-34mg/day (Sufficient to meet all needs!) Dietary L-Carnitine Red meat, dairy, fish, wheat, asparagus, avocado Omnivorous diet: 20-200mg/day (~75% absorbed) No proof of Dietary need exists L-Carnitine as a Supplement Liquid form,Tablets & Capsules Typical Dose: 1000-6000 mg/day ~20% absorbed by the body Generally non-toxic Intended population: Athletes Dieters Purported Benefits Primary Systemic Carnitine Deficiency A recessive gene mutation Cardiovascular Disease Alzheimers Disease Chronic Fatigue In the Elderly Population In Cancer Patients Fat Loss No Evidence EXERCISE PERFORMANCE

Acosta, L., Byham-Gray, L., Kurzer, M., & Samavat, H