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Chronic Obstructive Pulmonary Disease (COPD) Chronic Obstructive Pulmonary Disease (COPD) Last Section Update: 12/2022 Contributor(s) : Shayna Sandhaus, PhD

excessive ROS caused reduced m and ATP levels, and impaired mitochondrial function with altered mitochondrial dynamics, exacerbating inflammatory response and promoting COPD progression ( Mitochondrial quality control is a regulatory mechanism for the bioenergetic changes that occur in response to mitochondrial dysfunction (Springer and Macleod, 2016)