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Then, IL-13 was used for the subsequent experiment

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KEAP1-NRF2 system as a potential therapeutic target in ALS The presence in ALS of increased levels of OS markers and impaired antioxidant defense in the brain and peripheral tissues [25] together with the central role of NRF2 in inducing target genes to counteract OS [272] make the KEAP1-NRF2 system a suitable therapeutic target for drugs and small molecules

However, such relationships are controversial and another study, performed at 3T failed to show positive correlations between Glx and GABA in visual and motor cortex 56