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Chemoproteomic studies using the active isomer of RSL3 as an affinity reagent identified the selenoprotein glutathione peroxidase 4 (GPX4, PHGPx) as a candidate target of this compound [6] (Fig

Although IVM does not affect the GABA system responsible for stimulating salivary fluid secretion, it may influence other GABA-mediated neural pathways in ticks 58