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The measurement of total iron binding capacity (TIBC) does not assist in the treatment of acute iron poisoning since it is falsely elevated in the face of high serum iron concentrations by some methods and since serum iron concentrations may be quickly changing in their relationship to TIBC

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The expansion of a G4C2 (GGGGCC) hexanucleotide repeat in the non-coding region leads to the production and accumulation of dipeptide repeat proteins in neurons (Maor-Nof et al., 2021)