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The nod, which converts a November 2022 accelerated approval, makes Elahere the first and only antibody-drug conjugate (ADC) approved in the U.S. for ovarian cancer, Roopal Thakkar, AbbVies CMO of global therapeutics, said in a statement

Research-use-only product is shipped in sealed lyophilised vials and should not be administered if the powder shows moisture, yellowing, or incomplete reconstitution

Once a diagnosis of hyperhomocysteinemia has been made, it is safe and easy to lower plasma tHcy in most individuals

Methylcobalamin is another non-prescription form popular in wellness settings, with more limited clinical evidence than hydroxocobalamin for treating true deficiency

For laboratory preparation it is reconstituted in water (listed solubility 1 mg/mL)