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1 Abbreviations Bio-GEE biotinylated glutathione ethyl ester DTT 1,4-dithiothreitol ETC electron transport chain GSH reduced glutathione GSSG oxidized glutathione LDH lactate dehydrogenase LPS lipopolysaccharide MitoCDNB Mitochondrially-targeted 1-chloro-2,4-dinitrobenzene NEM N-ethylmaleimide OGDHC 2-oxoglutarate dehydrogenase complex PDC pyruvate dehydrogenase complex PDCE2 PDC E2 component PDCE3 PDC E3 component ROS reactive oxygen species SDS-PAGE sodium dodecyl sulfate-polyacrylamide gel electrophoresis TLR toll-like receptor.