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Description

Abstract Parkinsons disease (PD) is a common neurodegenerative disorder caused by a spread of misfolded -synuclein and ascending neuronal degeneration mainly in dopaminergic neurons, leading to progressive nigrostriatal dysfunction and disruption of other pathways

First, under conditions of nutritional ketosis, -HB constitutes the principal KB in systemic circulation, representing the majority of the dynamic range in circulating ketone concentrations