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That means when temperatures outside drop, your body must burn more fuel just to keep you warm

(2020) 181:126375 e16

Based on these properties, AAV9 was investigated in mice models of spinal muscular atrophy (SMA), a monogenic disease characterized by the degeneration of the spinal motor neurons, with positive results in motor neuron survival, reversal of the phenotype and increased survival (Dominguez et al