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Genetic testing for non- HFE variants is available in specialized centers ( HAMP, HJV, TFR2, TF, CP, BMP6, SCL40A1 ) and discussions with personnel experienced in this field is important to evaluate the likelihood that any identified variants of genes of interest are pathogenic [13]

Besteht eine erhhte entzndliche oder oxidative Belastung

Dysregulation of these genes exacerbates oxidative stress damage and DNA damage while impairing normal cellular functions, thereby promoting the development and progression of ARC (43,108,235-237,243,275,278,285,290) (Fig