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Mayatepek E, Hoffmann GF, Carlsson B, Larsson A, Becker K: Impaired synthesis of lipoxygenase products in glutathione synthetase deficiency

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Therefore, we explored the ferroptosis regulation of SCD erythroblasts under physiological cystine supplementation

The resulting oxidized form of GSH either reacts with another GSH molecule to form GSSG or with cysteine groups on cellular proteins to form protein GSH mixed disulfides, a process known as protein glutathionylation. This latter reaction can change the proteins structure and function, which can, in turn, evoke a functional change within the cell

And, while it does look at many different markers that point to different kinds of imbalances, there are a number of important drivers of chronic disease that OAT tests dont test for directly