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Description

137 Upon breaching the basement membrane and entering the mesenchyme, the neutrophil transitions to an amoeboid mode of migration, characterized by cellular deformation, actin polymerization, and the reorganization of surrounding tissue structures

In accordance with this, it was shown that mutp53 can reestablish canonical p53 transcriptional activity over a particular set of genes, such as GLS1, CDKN1A, GAGG45A, and TIGAR, favoring new adaptive mechanisms for stress conditions (Tran et al., 2017