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Additionally, A deposition also led to lipid peroxidation and ROS generation

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FIGURE 3 Tumor treatment Wang et al

High glucose and high lipid (HGHL)- induced OS causes osteoblast failure by reducing Nrf2 signaling through the AKT/GSK3/FYN pathway

Likewise, results obtained in various diet-induced MASLD/MASH rodent models revealed a marked reduction in CAT activity in the serum as well as the liver of these animals as compared to respective controls (Dai et al

The present review summarizes ferroptosis-related mechanisms across AD, PD and DACI, emphasizing both the common molecular features and the unique triggers in each disease