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We then conducted association analyses between FRG subtypes and various tumor microenvironment (TME) characteristics, traditional key transcript factor subtypes, clinical features, transcriptional and post-transcriptional regulation, drug response, and the efficacy of immunotherapy

Conclusion Glutamine is the most abundant amino acid in plasma, and its metabolism, as a central part of cancer metabolic reprogramming, provides energy support for cancer cells and promotes proliferation, invasion, metastasis, and immune escape

Moreover, APOE4 exhibits a higher binding affinity for Sirt1 when compared with APOE3 and APOE2 (Lima et al

Saw et al., 2024)