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Results and discussion Modified dDAT resembles hNET primary substrate-binding site The dDAT, much like its human counterparts hDAT and hNET, is capable of interacting with both DA ( K i = 2.0 M) and NE ( K i = 19.1 M) with varying efficacies (Fig

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Several studies over the years showed that PR is able to promote lifespan and healthspan extension in mice (Pamplona and Barja, 2006), consolidating PR as a promising anti-aging intervention